Working group: Fats, Surfactants, Cosmetics
Pedagogical activity:
- Introduction to Food and Biochemical Sciences (for BSc degree)
- Basics Cosmetics (for BSc degree)
- Chemistry and Technology of Cosmetics (for MSc degree)
- Food Production and Nutritional Value (for MSc degree)
- Technological Project (for MSc degree)
- Supervising MSc diploma projects (25 students)
Scientific activity:
- Use of active compounds in cosmetic products
- Skin surface lipid composition
- Penetration of cosmetic ingredients into the skin, determined by an ex vivo method
- Physical, chemical and microbiological stability of emulsions
- Antioxidative effects of phenolic acids
- Oxidative stability fat-dispersive systems (emulsions and other fat-dispersal systems). Determination of oil and fat oxidation stability using Rancimat and Oxidograph
- Use of SPME, headspace sampling, GC-MS, GC-FID and HPLC in analysis of lipids
Education:
- 1997 – 2002 Institute of Chemical Technology, Prague, Dairy and Fat Technology
- 2002 – 2006 PGS, Institute of Chemical Technology, Prague, Food Technology
Employment history:
- 2005 – 2006 Research Assistant, Institute of Chemical Technology, Prague, Department of Dairy and Fat Technology
- 2006 – 2021 Assistant Professor, Institute of Chemical Technology, Prague, Department of Dairy and Fat Technology
- 2021 - Associate Professor, University of Chemical Technology, Prague, Department of Dairy, Fat and Cosmetics
Selected scientific papers since 2015:
ORCID ID 0000-0001-9893-1767- Xavier-Souza, J. F.; Siqueira, R. A. G. B.; Moreira, B. S.; Barbosa, S. G.; Mariano, E. S. N.; Marinotti, L. I.; Costa, I. G.; Requena, B. S.; Lima, T. P.; Hradkova, I.; et al. Understanding the Impact of the Skin Microbiome on Dermatological Assessments and Therapeutic Innovation. Dermato 2025, 5 (4), 21. DOI: 10.3390/dermato5040021.
- Sasínová, K.; Berčíková, M.; Vrchotová, B.; Hrádková, I.; Šmidrkal, J.; Kalenchak, K. Antimicrobial and Biofilm Inhibition Activity of Novel Biobased Quaternary Ammonium Salts. ACS Omega 2025, 10 (34), 39236-39249. DOI: 10.1021/acsomega.5c06267.
- Siqueira, R. A. G. B.; Hradkova, I.; Leite-Silva, V. R.; Andréo-Filho, N.; Lopes, P. S. Skin Lipids and Their Influence on Skin Microbiome and Skin Care. ACS Omega 2025, 10 (27), 28534-28546. DOI: 10.1021/acsomega.4c11687.
- Feldeková, E.; Kosová, M.; Berčíková, M.; Dragoun, M.; Klojdová, I.; Hrádková, I.; Šmidrkal, J. Antimicrobial properties of phenolic acid alkyl esters. Czech Journal of Food Sciences 2022, 40 (6), 438-444. DOI: 10.17221/135/2022-CJFS.
- Berčíková, M.; Lád, J.; Hrádková, I.; Kumherová, M.; Šmidrkal, J. Reaction of Fatty Acid Methyl Ester with Monoethanolamine and Diethanolamine. Tenside Surfactants Detergents 2021, 58 (4), 287-292. DOI: 10.1515/tsd-2020-2328.
- Hradkova, I.; Kumherova, M.; Smidrkal, J. Preservatives in Cosmetics. Chemicke Listy 2021, 115 (10), 554-556.
- Kyselka, J., K. Cihelková, D. Lopes-Lutz, J. Chudoba, T. Váchalová, K. Alishevich, I. Hrádková, M. Berčíková, M. Mikolášková, and V. Filip. "Mechanism Controlling High-Temperature Degradation of Sunflower Oil Triacylglycerols in the Absence of Oxygen." Article, European Journal of Lipid Science and Technology 123, no. 3 (2021). doi:10.1002/ejlt.202000228.
- Berčíková, M., A. Šimková, K. Hudecová, J. Kyselka, V. Filip, and I. Hrádková. "Physical Properties of Structured Fats and Fat Blends Based on the Long Chain Fatty Acids." Article, Food Biophysics 15, no. 1 (2020): 143-52. doi:10.1007/s11483-019-09609-8.
- Kyselka, J., T. Honzíková, T. Váchalová, T. Jirásková, K. Alishevich, Z. Rottnerová, V. Brychová, M. Berčíková, I. Hrádková, and V. Filip. "Formation of 5α-Sitostan-3-One, 5α-Campestan-3-One, and Steroidal Hydrocarbons in Edible Oils During Catalytic Hydrogenation." Article, Journal of Agricultural and Food Chemistry 67, no. 35 (2019): 9916-25. doi:10.1021/acs.jafc.9b03054.
- Paskova L., Kuncírová V., Poništ S., Mihálová D., Nosál R., Harmatha J., Hrádková I., Havojský T., Bilka F., Šišková K., Paulíková I., Bezáková L., Bauerová K.: "Effect of N-Feruloylserotonin and Methotrexate on Severity of Experimental Arthritis and on Messenger RNA Expression of Key Proinflammatory Markers in Liver." Journal of Immunology Research 2016, Article ID 7509653, DOI: 10.1155/2016/7509653
- Smidrkal, Tesarova, M., Hradkova, I., Bercikova, M., Adamcikova, A., & Filip, V. (2016): "Mechanism of formation of 3-chloropropan-1,2-diol (3-MCPD) esters under conditions of the vegetable oil refining." Food Chemistry 211: 124-129 . DOI: 10.1016/j.foodchem.2016.05.039
- Kosová M., Hrádková I., Mátlová V., Kadlec D., Šmidrkal J., Filip V.: Antimicrobial effect of 4-hydroxybenzoic acid ester with glycerol. J Clin Pharm Ther.40, 436-440 (2015). doi: 10.1111/jcpt.12285